Category Archives: Molecular

Validation of Cell-Based Assays in the GLP Setting: A Practical Guide

The use of cell-based assays within pharmaceutical and biotechnology companies is driven in large part by the need to evaluate the plethora of drug targets derived from genomics and proteomics. In addition, the potential of biomarkers to facilitate the development … Continue reading

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Drug Design: Cutting Edge Approaches

Pharmaceutical research draws on increasingly complex techniques to solve the challenges of drug design. Bringing together a number of the latest informatics techniques, this book looks at modelling and bioinformatic strategies; structural genomics and X-ray crystallography; virtual screening; lead optimisation; … Continue reading

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Novel Anticancer Drug Protocols (Methods in Molecular Medicine) (Methods in Molecular Biology)

Univ. of Tennessee, Memphis. Text provides a broad range of cutting-edge methodologies currently being used in the discovery and development of novel anti-cancer drugs. Discusses kinase inhibitor protocols, angiogenesis and metastasis protocols, and chaperoning/degradation protocols. For clinicians and researchers.

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Apoptosis Methods in Pharmacology and Toxicology: Approaches to Measurement and Quantification

Univ. of Maryland, Baltimore. Discusses laser scanning cytometry for the analysis of apoptosis, tissue-based methods of quantification for studies using animal models, and functional assays and ELISA techniques. DNLM: Apoptosis–physiology.

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High Throughput Screening: Methods and Protocols (Methods in Molecular Biology) (Methods in Molecular Biology, 190)

In High Throughput Screening, leading scientists and researchers expert in molecular discovery explain the diverse technologies and key techniques used in HTS and demonstrate how they can be applied generically. Writing to create precisely the introductory guidebook they wish had … Continue reading

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Molecular Bases of Anesthesia (Handbooks in Pharmacology and Toxicology)

Molecular Bases of Anesthesia provides a clear overview of the state of knowledge about anesthetic mechanisms at the molecular level of occurrence and focusing on the latest state-of-the-art techniques that relate to how anesthetic drugs cause unconsciousness. With contributions by … Continue reading

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Drug-Dna Interaction Protocols (Methods in Molecular Biology)

Univ. of Southampton, U.K. Discusses the molecular techniques that illuminate and explore the interaction of drugs and ligands with DNA. 33 contributors, 21 U.S.

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Particle Size Analysis In Pharmaceutics And Other Industries: Theory And Practice (Ellis Horwood Books in the Biological Sciences)

Recent major advances in particle size analysis, particularly with regard to its application in the pharmaceutical and related industries, provides justification for this title. It is a book for technicians and senior technicians, project and development managers, and formulation development … Continue reading

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