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Category Archives: Product Development
Preclinical Development Handbook: Toxicology (Pharmaceutical Development Series)
A clear, straightforward resource to guide you through preclinical drug development Following this book’s step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic,comprehensive reference to prioritizing and optimizing leads, … Continue reading
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Drug Absorption Studies: In Situ, In Vitro and In Silico Models (Biotechnology: Pharmaceutical Aspects)
In the last 15 years, a great number of cell- or tissue-based in vitro models have been introduced into the biopharmaceutics arena. These models mimic the different biological barriers that a drug has to overcome to finally reach its target … Continue reading
Validation of Cell-Based Assays in the GLP Setting: A Practical Guide
The use of cell-based assays within pharmaceutical and biotechnology companies is driven in large part by the need to evaluate the plethora of drug targets derived from genomics and proteomics. In addition, the potential of biomarkers to facilitate the development … Continue reading
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The Handbook of Nanomedicine
Nanomedicine is clinical medicine with the application of nanobiotechnology, which is currently being used to research the pathomechanism of disease, refine molecular diagnostics, and aid in the discovery, development and delivery of drugs. In The Handbook of Nanomedicine, Prof. Kewal … Continue reading
Post-translational Modifications of Proteins: Tools for Functional Proteomics (Methods in Molecular Biology)
The majority of all proteins undergo co- and/or post-translational modifications, crucially altering physical and chemical properties, folding, conformation distribution, stability, activity, and, consequently, the function of the proteins. In Post-translational Modifications of Proteins: Tools for Functional Proteomics, Second Edition, this … Continue reading
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Drug Targets in Kinetoplastid Parasites (Advances in Experimental Medicine and Biology)
If viewed globally, the parasitic diseases pose an increasing threat to human health and welfare. The diseases caused by kinetoplastid protozoan parasites like Leishmania and Trypanosoma continue as a cause of suffering for many millions of people in both tropical … Continue reading
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Drug Delivery Systems (Methods in Molecular Biology)
The field of drug development and therapeutics can be overwhelmingly encyclopedic and vast. In Drug Delivery Systems, Dr. Kewal Jain and a team of experts select the most important, cutting-edge technologies used in drug delivery systems taking into account significant … Continue reading
New Avenues to Efficient Chemical Synthesis: Emerging Technologies (Ernst Schering Foundation Symposium Proceedings)
In modern drug discovery and development, chemical synthesis is one of the key technologies. For the rapid preparation of new test compounds and drug development candidates, several innovative technologies with great potential have emerged: Microreactor chemistry; Nanotechnology and catalysis research; … Continue reading
The Process of New Drug Discovery and Development, Second Edition
The Process of New Drug Discovery and Development, Second Edition presents a practical methodology and up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. This new addition updates … Continue reading
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Integrated Strategies for Drug Discovery Using Mass Spectrometry
New strategies and techniques for today’s fast-paced discovery process Today, the pressure is on for high-throughput approaches to accelerate the generation, identification, and optimization of molecules with desirable drug properties. As traditional methods of analysis become antiquated, new analytical strategies … Continue reading